2747996-65-0

rel-A-395 hydrochloride Chemical Structure
2747996-65-0

Chemical Structure

rel-A-395 hydrochloride

  • CAS No.: 2747996-65-0
  • Formula:C26H36ClFN4O2S
  • Molecular Weight:523.11

InChIKey: JUZXQLNCGDDSMJ-NNEMXYTISA-N

SMILES: O=S(N1CCN(C2=CC=C([C@H]3CN(C4C(C(F)=CC=C5)=C5CC4)C[C@@H]3N(C)C)C=C2)CC1)(C)=O.Cl

Biological Activity: rel-A-395 hydrochloride is the relative configuration of A-395 (HY-101512) hydrochloride. A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-101512D 		rel-A-395 hydrochloride rel-A-395 hydrochloride is the relative configuration of A-395 (HY-101512) hydrochloride. A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.
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