2761947-05-9
Chemical Structure
M24
- CAS No.: 2761947-05-9
- Formula:C44H40Cl3N5O11S
- Molecular Weight:953.24
IUPAC Name: 2-(2-(3-(4-(2-(4-chloro-3,5-dimethylphenoxy)ethoxy)benzyl)-2,5-dioxoimidazolidin-1-yl)acetamido)-N-((4-chloro-3-nitrophenyl)sulfonyl)-3-(4-((4-chlorobenzyl)oxy)phenyl)propanamide
InChIKey: BBCRCNRTBDZUKL-UHFFFAOYSA-N
SMILES: CC1=CC(OCCOC2=CC=C(C=C2)CN3CC(N(C3=O)CC(NC(C(NS(=O)(C4=CC([N+]([O-])=O)=C(C=C4)Cl)=O)=O)CC5=CC=C(C=C5)OCC6=CC=C(C=C6)Cl)=O)=O)=CC(C)=C1Cl
Biological Activity: M24 is a Mcl-1 selective inhibitor. M24 exhibits good binding affinity against Mcl-1 with Ki value of 0.33 μM. M24 exhibits good anti-proliferative activity and induce apoptosis in HepG2 cells[1].
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M24 | M24 is a Mcl-1 selective inhibitor. M24 exhibits good binding affinity against Mcl-1 with Ki value of 0.33 μM. M24 exhibits good anti-proliferative activity and induce apoptosis in HepG2 cells. | |||||||||||||||||||||
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Keywords
