2762043-61-6
2762043-61-6
Chemical Structure
BTK-IN-26
- CAS No.: 2762043-61-6
- Formula:C27H26D3FN6O3
- Molecular Weight:507.57
InChIKey: JIURUZAXNKNUJW-IFPIUMIYSA-N
SMILES: NC1=NC=NN2C([C@@H]3CC[C@H](CC3)CO)=NC(C4=CC=C(C=C4)CNC(C5=C(C=CC(F)=C5)OC([2H])([2H])[2H])=O)=C12
Biological Activity: BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].
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BTK-IN-26 | BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research. | |||||||||||||||||||||
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References
Keywords
