2763085-07-8
Chemical Structure
7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine
- CAS No.: 2763085-07-8
- Formula:C14H19N5O6
- Molecular Weight:353.33
IUPAC Name: 2-amino-7-(cyclopropylmethyl)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purine-6,8-dione
InChIKey: NJMSVNBCVHFPMM-WOUKDFQISA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N(C(N2CC3CC3)=O)C4=C2C(NC(N)=N4)=O)O[C@@H]1CO
Biological Activity: 7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine | 7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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