2763260-36-0
2763260-36-0
Chemical Structure
NRX-103094
- CAS No.: 2763260-36-0
- Formula:C20H11Cl2F3N2O4S
- Molecular Weight:503.28
IUPAC Name: 3-(4-((2,6-dichlorophenyl)thio)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamido)benzoic acid
InChIKey: HFBGFWJURBVNFD-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl)=O)=C1)=O
Biological Activity: NRX-103094 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NRX-103094 | 99.89% | NRX-103094 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM. | ||||||||||||||||||||
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References
Keywords
