2766131-24-0
2766131-24-0
Chemical Structure
Lepodisiran sodium
Synonym(s): LY3819469 sodium
- CAS No.: 2766131-24-0
- Formula:N/A
- Molecular Weight:21973.00
SMILES: [Lepodisiran (sodium)]
Biological Activity: Lepodisiran (LY3819469) sodium is a GalNAc-conjugated small interfering RNA lipid-lowering agent. Lepodisiran sodium targets the hepatic LPA gene and degrades apolipoprotein (a) mRNA to silence its expression, thereby effectively reducing the production of apolipoprotein (a) and serum lipoprotein (a) in a dose-dependent manner. Lepodisiran sodium can be used in studies related to atherosclerotic cardiovascular disease[1].
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Lepodisiran sodium | Lepodisiran (LY3819469) sodium is a GalNAc-conjugated small interfering RNA lipid-lowering agent. Lepodisiran sodium targets the hepatic LPA gene and degrades apolipoprotein (a) mRNA to silence its expression, thereby effectively reducing the production of apolipoprotein (a) and serum lipoprotein (a) in a dose-dependent manner. Lepodisiran sodium can be used in studies related to atherosclerotic cardiovascular disease. | |||||||||||||||||||||
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