2766209-50-9
2766209-50-9
Chemical Structure
TH-Z835
- CAS No.: 2766209-50-9
- Formula:C30H38N6O
- Molecular Weight:498.66
IUPAC Name: 4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
InChIKey: KIWVGCSJQTTZJO-VXNXHJTFSA-N
SMILES: CN(CCC1)[C@@H]1COC2=NC(N3C[C@H]4N[C@H](CC4)C3)=C5C(CN(C6=CC=CC7=C6C(C)=CC=C7)CC5)=N2
Biological Activity: TH-Z835 is a mutant selective KRAS (G12D) inhibitor with an IC50 of 1.6 μM. TH-Z835 inhibits both mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TH-Z835 | 99.58% | TH-Z835 is a mutant selective KRAS (G12D) inhibitor with an IC50 of 1.6 μM. TH-Z835 inhibits both mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange. | ||||||||||||||||||||
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References
Keywords
