2766451-11-8
Chemical Structure
P-gp inhibitor 3
- CAS No.: 2766451-11-8
- Formula:C48H67N3O6
- Molecular Weight:782.06
IUPAC Name: benzyl (4aS,6aS,6bR,8aR,9R,13aR,13bR,15bS)-9-(((4-(4-ethylpiperazin-1-yl)-4-oxobutanoyl)oxy)methyl)-2,2,6a,6b,9,13a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,13,13a,13b,14,15b-hexadecahydropiceno[2,3-d]isoxazole-4a(2H)-carboxylate
InChIKey: XDMZDNVQHFRLSA-QJSWLHHPSA-N
SMILES: O=C([C@]12[C@](CC(C)(CC2)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)(C5=C(C=NO5)C4)COC(CCC(N6CCN(CC6)CC)=O)=O)([H])CC7)C)([H])[C@]7(C)[C@@]3(CC1)C)OCC8=CC=CC=C8
Biological Activity: P-gp inhibitor 3 is an effective P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 3 inhibits the efflux function of P-gp by activating P-gp ATPase. P-gp inhibitor 3 has relatively stronger multidrug resistance (MDR) reversal ability and enhances the anti-tumor activity of Paclitaxel[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
P-gp inhibitor 3 | P-gp inhibitor 3 is an effective P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 3 inhibits the efflux function of P-gp by activating P-gp ATPase. P-gp inhibitor 3 has relatively stronger multidrug resistance (MDR) reversal ability and enhances the anti-tumor activity of Paclitaxel. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
