2768181-63-9
2768181-63-9
Chemical Structure
PI3Kδ-IN-17
- CAS No.: 2768181-63-9
- Formula:C23H24F3N7O2
- Molecular Weight:487.48
InChIKey: TXUGKPGKQQLPNM-KSSFIOAISA-N
SMILES: O=C(N1C[C@@H](NC2=C3C(C=CC(C4=CC(C(F)(F)F)=C(OC)N=C4)=N3)=NC=N2)CC1)[C@H]5NCCC5
Biological Activity: PI3Kδ-IN-17 (Compound S5) is a potent inhibitor of PI3Kδ, with IC50 of 2.82?nM. PI3Kδ-IN-17 shows strong inhibitory activity of proliferation in SU-DHL-6 cells (IC50 = 0.035 μM)[1].
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PI3Kδ-IN-17 | PI3Kδ-IN-17 (Compound S5) is a potent inhibitor of PI3Kδ, with IC50 of 2.82?nM. PI3Kδ-IN-17 shows strong inhibitory activity of proliferation in SU-DHL-6 cells (IC50 = 0.035 μM). | |||||||||||||||||||||
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References
Keywords
