2769753-49-1
2769753-49-1
Chemical Structure
FLT3 Ligand-Linker Conjugate 1
- CAS No.: 2769753-49-1
- Formula:C29H34N6O4S2
- Molecular Weight:594.75
SMILES: CS(NC1=CC=CC(C2=CSC3=CN=C(N=C23)NC4=CC=C(N5CCN(CC5)CCCCCC(O)=O)C=C4)=C1)(=O)=O
Biological Activity: FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680 (HY-148062). PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases[1].
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FLT3 Ligand-Linker Conjugate 1 | FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680 (HY-148062). PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases. | |||||||||||||||||||||
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References
Keywords
