2770246-12-1
2770246-12-1
Chemical Structure
HSD17B13-IN-48
- CAS No.: 2770246-12-1
- Formula:C23H16Cl2FN3O3
- Molecular Weight:472.30
InChIKey: NJKMJALOBLNOQC-LBPRGKRZSA-N
SMILES: FC1=CC([C@H](C)N2C=NC3=CC=CC(NC(C4=CC(Cl)=C(O)C(Cl)=C4)=O)=C3C2=O)=CC=C1
Biological Activity: HSD17B13-IN-48 (Compound 12) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-48 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-48 | HSD17B13-IN-48 (Compound 12) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-48 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
