2770246-42-7
Chemical Structure
HSD17B13-IN-28
- CAS No.: 2770246-42-7
- Formula:C23H16Cl2FN3O3
- Molecular Weight:472.30
InChIKey: NJKMJALOBLNOQC-GFCCVEGCSA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=C3C(N=CN(C3=O)[C@@H](C4=CC(F)=CC=C4)C)=CC=C2
Biological Activity: HSD17B13-IN-28 (compound? 47) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-28? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].
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HSD17B13-IN-28 | HSD17B13-IN-28 (compound? 47) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-28? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis). | |||||||||||||||||||||
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Keywords