2770247-20-4
2770247-20-4
Chemical Structure
HSD17B13-IN-60
- CAS No.: 2770247-20-4
- Formula:C20H16Cl2FN3O3S
- Molecular Weight:468.33
InChIKey: RAOZBUGERNTVQA-VIFPVBQESA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=C(C(C)=NS2)C(N[C@H](C3=C(C=CC=C3)F)C)=O
Biological Activity: HSD17B13-IN-60 (Compound 126) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-60 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-60 | HSD17B13-IN-60 (Compound 126) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-60 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
