2770247-41-9
2770247-41-9
Chemical Structure
HSD17B13-IN-83
- CAS No.: 2770247-41-9
- Formula:C23H14Cl2F4N4O4
- Molecular Weight:557.28
InChIKey: MBENCCPOMIIMPQ-UHFFFAOYSA-N
SMILES: O=C(C1=NC(Cl)=C(C(Cl)=C1)O)NC2=CC=C(C(N=C(C)N3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O)F
Biological Activity: HSD17B13-IN-83 (Compound 150) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-83 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-83 | HSD17B13-IN-83 (Compound 150) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-83 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
