2770247-49-7
2770247-49-7
Chemical Structure
HSD17B13-IN-54
- CAS No.: 2770247-49-7
- Formula:C24H15Cl2F4N3O3
- Molecular Weight:540.29
InChIKey: GFTZAKCFKZQRBD-UHFFFAOYSA-N
SMILES: OC1=C(Cl)C=C(C(NC2=CC=C(F)C(N=C(C)N3CC4=CC=CC=C4C(F)(F)F)=C2C3=O)=O)C=C1Cl
Biological Activity: HSD17B13-IN-54 (Compound 158) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-54 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-54 | HSD17B13-IN-54 (Compound 158) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-54 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
