2770247-59-9
2770247-59-9
Chemical Structure
HSD17B13-IN-65
- CAS No.: 2770247-59-9
- Formula:C24H15Cl2F4N3O4
- Molecular Weight:556.29
InChIKey: RBOVPHNKKHUJMC-UHFFFAOYSA-N
SMILES: OC1=C(C=C(C=C1Cl)C(NC2=CC=C(C(N=C(N3CC4=CC=CC=C4OC(F)(F)F)C)=C2C3=O)F)=O)Cl
Biological Activity: HSD17B13-IN-65 (Compound 168) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-65 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-65 | HSD17B13-IN-65 (Compound 168) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-65 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
