2791286-89-8
2791286-89-8
Chemical Structure
Thalidomide-piperazine-C-azetidine TFA
- CAS No.: 2791286-89-8
- Formula:C23H26F3N5O6
- Molecular Weight:525.48
IUPAC Name: 5-(4-(azetidin-3-ylmethyl)piperazin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
InChIKey: TWACKOSSUZFZHL-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CNC5)CC4)C=C3C2=O)=O)=O.O=C(C(F)(F)F)O
Biological Activity: Thalidomide-piperazine-C-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Thalidomide-piperazine-C-azetidine TFA | Thalidomide-piperazine-C-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC. | |||||||||||||||||||||
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