2820126-28-9

EGFR/HER2-IN-7 Chemical Structure
2820126-28-9

Chemical Structure

EGFR/HER2-IN-7

  • CAS No.: 2820126-28-9
  • Formula:C19H21N3O2S
  • Molecular Weight:355.45

IUPAC Name: 6-(piperidin-1-ylmethyl)-5-(p-tolyl)imidazo[2,1-b]thiazole-3-carboxylic acid

InChIKey: PGZHYLDDJOVDMW-UHFFFAOYSA-N

SMILES: O=C(C1=CSC2=NC(CN3CCCCC3)=C(C4=CC=C(C)C=C4)N21)O

Biological Activity: EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR/HER2 kinase and DHFR inhibitor, with IC50s of 0.18 μM (EGFR), 0.146 μM (HER2), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR (IC50=0.907 μM)[1].

Cat. No. Product Name Purity Description Pricing
HY-151158 		EGFR/HER2-IN-7 EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR/HER2 kinase and DHFR inhibitor, with IC50s of 0.18 μM (EGFR), 0.146 μM (HER2), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR (IC50=0.907 μM).
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