2825006-38-8
Chemical Structure
Thalidomide-5-methanol
- CAS No.: 2825006-38-8
- Formula:C14H12N2O5
- Molecular Weight:288.26
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-(hydroxymethyl)isoindoline-1,3-dione
InChIKey: UWVIUWWWHIAFLY-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)CO
Biological Activity: Thalidomide-5-methanol is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-methanol can be linked to a target protein ligand via a linker to form a PROTAC.
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Thalidomide-5-methanol | Thalidomide-5-methanol is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-methanol can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords