2832199-45-6
Chemical Structure
TLR7 agonist 14
- CAS No.: 2832199-45-6
- Formula:C29H36N6O3
- Molecular Weight:516.63
InChIKey: QLONMNKKVKTOHQ-UHFFFAOYSA-N
SMILES: O=C(NCCC(NC1=CC=C(CN2C(CCCC)=NC3=C2C4=C(C=CC=C4)N=C3N)C=C1)=O)OC(C)(C)C
Biological Activity: TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].
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TLR7 agonist 14 | TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations. | |||||||||||||||||||||
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Keywords