2836996-95-1
2836996-95-1
Chemical Structure
DPP IV/hCA II-IN-1
- CAS No.: 2836996-95-1
- Formula:C17H20N2O5S
- Molecular Weight:364.42
IUPAC Name: 4-(3-amino-3-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)propoxy)benzenesulfonamide
InChIKey: GHVPEVBTYVRTHA-UHFFFAOYSA-N
SMILES: NC(C1COC2=CC=CC=C2O1)CCOC3=CC=C(C=C3)S(=O)(N)=O
Biological Activity: DPP IV/hCA II-IN-1 is a potent and selective dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA) inhibitor with an IC50 value of 0.049 μM for DPP IV and with Ki values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and 3.034 μM for CA II, CA VB, CA VA, CA IX, CA I, and CA IV, respectively[1].
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DPP IV/hCA II-IN-1 | DPP IV/hCA II-IN-1 is a potent and selective dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA) inhibitor with an IC50 value of 0.049 μM for DPP IV and with Ki values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and 3.034 μM for CA II, CA VB, CA VA, CA IX, CA I, and CA IV, respectively. | |||||||||||||||||||||
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References
Keywords
