2839311-21-4

mHTT-IN-1 Chemical Structure
2839311-21-4

Chemical Structure

mHTT-IN-1

  • CAS No.: 2839311-21-4
  • Formula:C18H19N7OS
  • Molecular Weight:381.45

IUPAC Name: 7-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-2-(piperazin-1-yl)-5H-thiazolo[3,2-a]pyrimidin-5-one

InChIKey: DSZATGYIYALKRF-UHFFFAOYSA-N

SMILES: O=C1C=C(C2=NN3C=C(C)N=C3C(C)=C2)N=C4SC(N5CCNCC5)=CN14

Biological Activity: mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-150245 		mHTT-IN-1 mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM.
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