2841710-23-2
2841710-23-2
Chemical Structure
Arachidonic acid leelamide
- CAS No.: 2841710-23-2
- Formula:C40H61NO
- Molecular Weight:571.92
InChIKey: PWAMXBSJCUBDIV-IARAYIMMSA-N
SMILES: C[C@@]12C3=CC=C(C(C)C)C=C3CC[C@@]1([H])[C@@](C)(CCC2)CNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
Biological Activity: Arachidonic acid leelamide, a Leelamine (HY-W005629) analog, is a pyruvate dehydrogenase kinase (PDK) inhibitor. Arachidonic acid leelamide can be used for the study of breast cancer[1][2].
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Arachidonic acid leelamide | Arachidonic acid leelamide, a Leelamine (HY-W005629) analog, is a pyruvate dehydrogenase kinase (PDK) inhibitor. Arachidonic acid leelamide can be used for the study of breast cancer. | |||||||||||||||||||||
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References
- [1]. Fiocchetti M, et al Dissecting the 17β-estradiol pathways necessary for neuroglobin anti-apoptotic activity in breast cancer. J Cell Physiol. 2018 Jul;233(7):5087-5103. [Content Brief]
- [2]. Aicher TD, et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK). Bioorg Med Chem Lett. 1999 Aug 2;9(15):2223-8. [Content Brief]
Keywords
