2848581-86-0
Chemical Structure
PTP1B-IN-16
- CAS No.: 2848581-86-0
- Formula:C26H18ClN3O4S
- Molecular Weight:503.96
IUPAC Name: 4-(2-((6-chloro-5-(naphthalen-2-yloxy)-1H-benzo[d]imidazol-2-yl)thio)acetamido)benzoic acid
InChIKey: FWMPLMANRSBOML-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)C(O)=O)CSC2=NC3=C(N2)C=C(C(OC4=CC5=CC=CC=C5C=C4)=C3)Cl
Biological Activity: PTP1B-IN-16 (Compound 46), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 12.6 μM. PTP1B-IN-16 can be used for the research of type 2 diabetes.
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PTP1B-IN-16 | PTP1B-IN-16 (Compound 46), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 12.6 μM. PTP1B-IN-16 can be used for the research of type 2 diabetes. | |||||||||||||||||||||
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Keywords