2861190-30-7
2861190-30-7
Chemical Structure
Mtb-IN-2
- CAS No.: 2861190-30-7
- Formula:C17H12N2O4
- Molecular Weight:308.29
InChIKey: WOVBYNARRLCBNS-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(O)=C(C(O)=O)C=C1)C2=NC3=C(C=C2)C=CC=C3
Biological Activity: Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
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Mtb-IN-2 | Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly. | |||||||||||||||||||||
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Keywords
