2891774-71-1
Chemical Structure
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol
- CAS No.: 2891774-71-1
- Formula:C31H30FN3O6
- Molecular Weight:559.58
InChIKey: NJOCUHWCWLJEOM-OXXUGIMDSA-N
SMILES: O=C1N2C(C3=NC4=CC(F)=C(C)C(CC5)=C4C([C@H]5NC(C67CC(C6)(C7)CO)=O)=C3C2)=CC([C@](O)8CC)=C1COC8=O
Biological Activity: Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA‑MB‑468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer[1].
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Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol | Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA‑MB‑468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer. | |||||||||||||||||||||
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