2892720-11-3
2892720-11-3
Chemical Structure
SDUY038
- CAS No.: 2892720-11-3
- Formula:C17H18Cl2N2O2S
- Molecular Weight:385.31
InChIKey: QIRSWHWANMQORU-UHFFFAOYSA-N
SMILES: O=C(N1CCC(C)(CC1)N)C2=CC=C(SC3=C(Cl)C(Cl)=CC=C3)O2
Biological Activity: SDUY038 is a SHP2 allosteric inhibitor, with an IC50 of 1.2 μM and KD of 0.29 μM, respectively. SDUY038 exhibits pan-antitumor activity (IC50 = 7-24 μM) by suppressing pERK expression. SDUY038 exhibits t1/2 of 3.95 h by oral administration[1].
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SDUY038 | SDUY038 is a SHP2 allosteric inhibitor, with an IC50 of 1.2 μM and KD of 0.29 μM, respectively. SDUY038 exhibits pan-antitumor activity (IC50 = 7-24 μM) by suppressing pERK expression. SDUY038 exhibits t1/2 of 3.95 h by oral administration. | |||||||||||||||||||||
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References
Keywords
