2905-15-9
Chemical Structure
Tubulin inhibitor 29
- CAS No.: 2905-15-9
- Formula:C12H8F2O2S2
- Molecular Weight:286.32
IUPAC Name: S-(4-fluorophenyl) 4-fluorobenzenesulfonothioate
InChIKey: RJGPLTZAVFXCME-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(F)C=C1)(SC2=CC=C(F)C=C2)=O
Biological Activity: Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].
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Tubulin inhibitor 29 | 98.85% | Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site. | ||||||||||||||||||||
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Keywords