2907782-78-7
2907782-78-7
Chemical Structure
AD1058
- CAS No.: 2907782-78-7
- Formula:C19H20N6O3S
- Molecular Weight:412.47
InChIKey: IJEDYDGSAXSVPY-GFCCVEGCSA-N
SMILES: O=S(N1C=CC2=C(N3[C@H](C)COCC3)N=C(C4=C5C(NC=C5)=NC=C4)N=C21)(C)=O
Biological Activity: AD1058 is an orally active, selective, and BBB-permeable inhibitor of ATR (IC50: 1.6 nM). AD1058 exhibits anticancer activity by inhibiting tumor cell proliferation, inducing cell cycle arrest, and promoting apoptosis. AD1058 is suitable for research on advanced malignancies and brain metastases[1].
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AD1058 | 98.04% | AD1058 is an orally active, selective, and BBB-permeable inhibitor of ATR (IC50: 1.6 nM). AD1058 exhibits anticancer activity by inhibiting tumor cell proliferation, inducing cell cycle arrest, and promoting apoptosis. AD1058 is suitable for research on advanced malignancies and brain metastases. | ||||||||||||||||||||
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References
Keywords
