2925069-71-0
Chemical Structure
CRBN ligand-644
- CAS No.: 2925069-71-0
- Formula:C14H11N3O4
- Molecular Weight:285.26
IUPAC Name: 7-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)isoquinoline-3-carboxylic acid
InChIKey: QALFFRAQJORDGM-UHFFFAOYSA-N
SMILES: O=C(O)C=1N=CC2=CC(=CC=C2C1)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-644 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-644 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-644 | CRBN ligand-644 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-644 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords