2925081-07-6
Chemical Structure
CRBN ligand-376
- CAS No.: 2925081-07-6
- Formula:C13H10BrN3O2
- Molecular Weight:320.15
IUPAC Name: 1-(8-bromoisoquinolin-6-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: XZJHVTNMUHCTON-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C=2C=C(Br)C=3C=NC=CC3C2
Biological Activity: CRBN ligand-376 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-376 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-376 | CRBN ligand-376 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-376 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords