2925081-22-5
2925081-22-5
Chemical Structure
CRBN ligand-374
- CAS No.: 2925081-22-5
- Formula:C13H12N4O2
- Molecular Weight:256.27
IUPAC Name: 1-(6-aminoisoquinolin-8-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: MTEINWWGJIHKPC-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C=2C=C(N)C=C3C=CN=CC32
Biological Activity: CRBN ligand-374 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-374 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-374 | CRBN ligand-374 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-374 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
