2925081-41-8
2925081-41-8
Chemical Structure
CRBN ligand-373
- CAS No.: 2925081-41-8
- Formula:C13H12N4O2
- Molecular Weight:256.27
IUPAC Name: 1-(3-aminoisoquinolin-6-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: XJPAIFJHLHMSBR-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C2=CC=C3C=NC(N)=CC3=C2
Biological Activity: CRBN ligand-373 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-373 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-373 | CRBN ligand-373 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-373 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
