2925089-83-2
Chemical Structure
CRBN ligand-357
- CAS No.: 2925089-83-2
- Formula:C11H9BrN4O2
- Molecular Weight:309.12
IUPAC Name: 1-(3-bromo-1H-indazol-7-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: RCNUXDDNBVZUDH-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C2=CC=CC=3C(Br)=NNC32
Biological Activity: CRBN ligand-357 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-357 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-357 | CRBN ligand-357 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-357 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords