2925095-61-8
Chemical Structure
CRBN ligand-489
- CAS No.: 2925095-61-8
- Formula:C14H11N3O4
- Molecular Weight:285.26
IUPAC Name: 8-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)quinoline-3-carboxylic acid
InChIKey: USXBHSPQURQBKM-UHFFFAOYSA-N
SMILES: O=C(O)C1=CN=C2C(C=CC=C2N3C(=O)NC(=O)CC3)=C1
Biological Activity: CRBN ligand-489 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-489 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-489 | CRBN ligand-489 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-489 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords