2944459-58-7
2944459-58-7
Chemical Structure
HDAC-IN-60
- CAS No.: 2944459-58-7
- Formula:C20H26N2O6
- Molecular Weight:390.43
InChIKey: OBSIQQGPKWGSIZ-UHFFFAOYSA-N
SMILES: COC1=C(OC)C(OC)=CC(CCC2=CC(NCC(NO)=O)=C(OC)C=C2)=C1
Biological Activity: HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
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HDAC-IN-60 | HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis. | |||||||||||||||||||||
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Keywords
