294868-24-9
294868-24-9
Chemical Structure
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine
- CAS No.: 294868-24-9
- Formula:C10H13FN2O4S
- Molecular Weight:276.28
IUPAC Name: 1-((2S,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: RCDAZGNPWLZONT-AYHNYZOXSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@H](F)[C@@H](N2C=C(C)C(NC2=O)=O)S1
Biological Activity: 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine | 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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