2952725-20-9
2952725-20-9
Chemical Structure
STAT6-IN-6
- CAS No.: 2952725-20-9
- Formula:C46H57F2N4O8PS3
- Molecular Weight:959.13
InChIKey: JNYHCJRVSVMUJF-PLHCNYJLSA-N
SMILES: O=C(N1CC(C2=CC=CC=C2)C(C1)C#N)[C@H]3N4[C@](CCCC[C@@H](C4=O)NC(C5=CC6=CC(C(F)(F)P(OCCSC(CC(C)C)=O)(OCCSC(CC(C)C)=O)=O)=CC=C6S5)=O)([H])CC3
Biological Activity: STAT6-IN-6 (compound 163) is a selective STAT6 inhibitor. STAT6-IN-6 selectively inhibits STAT6 phosphorylation, with IC50s of ≤100nM and >3μM for pSTAT6 and pSTAT3, respectively. STAT6-IN-6 can be used for the study of cancer and inflammatory diseases[1].
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STAT6-IN-6 | STAT6-IN-6 (compound 163) is a selective STAT6 inhibitor. STAT6-IN-6 selectively inhibits STAT6 phosphorylation, with IC50s of ≤100nM and >3μM for pSTAT6 and pSTAT3, respectively. STAT6-IN-6 can be used for the study of cancer and inflammatory diseases. | |||||||||||||||||||||
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References
Keywords
