2965703-02-8
2965703-02-8
Chemical Structure
RET-IN-25
- CAS No.: 2965703-02-8
- Formula:C22H17N3O5S
- Molecular Weight:435.45
InChIKey: DJUVEFGKMOGMIX-UHFFFAOYSA-N
SMILES: O=C(NC1=C(SC2=C1C=NC3=CC=C(C=C32)[N+]([O-])=O)C(OCC)=O)C4=CC=C(C)C=C4
Biological Activity: RET-IN-25 (compound 6b) is a RET kinase inhibitor with anticancer activity. RET-IN-25 inhibits medullary thyroid carcinoma (MTC) with IC50s of 3.6 μM (3 days) and 3.0 μM (6 days) against TT(C634R) MTC[1].
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RET-IN-25 | RET-IN-25 (compound 6b) is a RET kinase inhibitor with anticancer activity. RET-IN-25 inhibits medullary thyroid carcinoma (MTC) with IC50s of 3.6 μM (3 days) and 3.0 μM (6 days) against TT(C634R) MTC. | |||||||||||||||||||||
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References
Keywords
