298217-59-1
Chemical Structure
MMV009085
- CAS No.: 298217-59-1
- Formula:C22H22N2O6
- Molecular Weight:410.42
IUPAC Name: 2,7-bis(4-hydroxybutyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone
InChIKey: XZBVMYTVRGGDKI-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C3C(N(CCCCO)C(C4=CC=C(C2=C34)C(N1CCCCO)=O)=O)=O
Biological Activity: MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MMV009085 | 98.68% | MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7). | ||||||||||||||||||||
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Keywords
