2982851-09-0
2982851-09-0
Chemical Structure
AK-068
- CAS No.: 2982851-09-0
- Formula:C31H36F2N3O7PS
- Molecular Weight:663.67
InChIKey: UOVVJNLEJYZVJE-JCYRPKCISA-N
SMILES: FC(C1=CC=C2C(C=C(C(N[C@@H](C(C)(C)C)C(N3[C@H](C(N4C[C@@H](C5=CC=CC=C5)OCC4)=O)CCC3)=O)=O)S2)=C1)(P(O)(O)=O)F
Biological Activity: AK-068 is a high-affinity and selective STAT6 ligand, with a Ki of 6 nM. AK-068 demonstrates at least >150- and >85-fold binding selectivity over STAT5A (Ki >1 μM) and STAT5B (Ki >500 μM) proteins, respectively. AK-068 is a ligand for target protein for PROTAC, can be used for synthesis of PROTACs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AK-068 | 99.57% | AK-068 is a high-affinity and selective STAT6 ligand, with a Ki of 6 nM. AK-068 demonstrates at least >150- and >85-fold binding selectivity over STAT5A (Ki >1 μM) and STAT5B (Ki >500 μM) proteins, respectively. AK-068 is a ligand for target protein for PROTAC, can be used for synthesis of PROTACs. | ||||||||||||||||||||
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References
Keywords
