2986412-70-6
2986412-70-6
Chemical Structure
ABCB1-IN-1
- CAS No.: 2986412-70-6
- Formula:C35H30F3FeN2O4PS
- Molecular Weight:718.50
InChIKey: UDUNDYJLSYXXIB-UHFFFAOYSA-M
SMILES: O=S([O-])(C(F)(F)F)=O.[O]#C[Fe+2]1234([CH-]5[CH]1=[CH]2[CH]3=[CH]45)([N](C=C6)=CN6CC7=CC=CC=C7)[P](C8=CC=CC=C8)(C9=CC=CC=C9)C%10=CC=CC=C%10
Biological Activity: ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively[1].
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ABCB1-IN-1 | ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively. | |||||||||||||||||||||
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References
Keywords
