2988301-08-0
2988301-08-0
Chemical Structure
Fmoc-Aeg(Dde)
- CAS No.: 2988301-08-0
- Formula:C29H32N2O6
- Molecular Weight:504.57
InChIKey: KDSJPUXOEQNZHT-UHFFFAOYSA-N
SMILES: O=C(CN(CCN/C(C)=C1C(CC(C)(CC\1=O)C)=O)C(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)O
Biological Activity: Fmoc-Aeg (Dde) is a protected aminoethylglycine (AEG) monomer used for solid-phase synthesis of peptide nucleic acids (PNAs). Fmoc-Aeg (Dde) contains the fluorenylmethoxycarbonyl (Fmoc) and 1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene) ethyl (Dde) protecting groups[1][2].
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Fmoc-Aeg(Dde) | Fmoc-Aeg (Dde) is a protected aminoethylglycine (AEG) monomer used for solid-phase synthesis of peptide nucleic acids (PNAs). Fmoc-Aeg (Dde) contains the fluorenylmethoxycarbonyl (Fmoc) and 1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene) ethyl (Dde) protecting groups. | |||||||||||||||||||||
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References
- [1]. Katkevics M, et al. Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs. Chem Commun (Camb). 2024;60(15):1999-2008. Published 2024 Feb 15. [Content Brief]
- [2]. Díaz-Mochón JJ, et al. Full orthogonality between Dde and Fmoc: the direct synthesis of PNA--peptide conjugates. Org Lett. 2004;6(7):1127-1129. [Content Brief]
Keywords
