3010931-91-3
Chemical Structure
AD011
- CAS No.: 3010931-91-3
- Formula:C27H33N3O5
- Molecular Weight:479.57
IUPAC Name: (S)-2-(((S)-1-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-1-oxohexan-2-yl)amino)-4-phenylbutanoic acid
InChIKey: YWBHCYRCVYEOPE-HJOGWXRNSA-N
SMILES: O=C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)CCCC)N[C@@H](CC2=CNC3=C2C=CC=C3)C(O)=O
Biological Activity: AD011 is a dual inhibitor of cACE/NEP. AD011 is synthesized based on the previously reported C-domain selective ACE inhibitor lisinopril-tryptophan. AD011 has the potential for providing the potent antihypertensive and cardioprotective benefits[1].
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AD011 | AD011 is a dual inhibitor of cACE/NEP. AD011 is synthesized based on the previously reported C-domain selective ACE inhibitor lisinopril-tryptophan. AD011 has the potential for providing the potent antihypertensive and cardioprotective benefits. | |||||||||||||||||||||
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Keywords