3023465-61-1
Chemical Structure
KRAS G12C-IN-76
- CAS No.: 3023465-61-1
- Formula:C38H33F4N7O2S
- Molecular Weight:727.77
InChIKey: SLPTUTIFIMSUSD-GGLHIIIUSA-N
SMILES: F[C@@H]1C[C@@](CCC2)(COC3=NC4=C(C(N5[C@H](CN(CC5)C(/C(F)=C/C6=NC=CS6)=O)C)=N3)C=NC(C7=C8C(C#C[H])=C(C=CC8=CC=C7)F)=C4F)N2C1
Biological Activity: KRAS G12C-IN-76 (Compound 39) is an orally active KRASG12C inhibitor. KRAS G12C-IN-76 inhibits the phosphorylation of ERK. KRAS G12C-IN-76 exhibits anticancer activity against pancreatic cancer[1].
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KRAS G12C-IN-76 | KRAS G12C-IN-76 (Compound 39) is an orally active KRASG12C inhibitor. KRAS G12C-IN-76 inhibits the phosphorylation of ERK. KRAS G12C-IN-76 exhibits anticancer activity against pancreatic cancer. | |||||||||||||||||||||
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Keywords