3030576-46-3
Chemical Structure
(1R)-KRAS inhibitor-24
- CAS No.: 3030576-46-3
- Formula:C33H39ClF2N6O3
- Molecular Weight:641.16
IUPAC Name: (13R)-33-chloro-28-fluoro-22-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-35-hydroxy-9-aza-2(4,7)-pyrido[4,3-d]pyrimidina-1(1,3)-piperidina-3(1,2)-benzenacycloundecaphan-8-one
InChIKey: LYQOAXNUFSGZPC-DIMBFDALSA-N
SMILES: C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCC(=O)NCC[C@@]5(CN2CCC5)[H])[C@@]67N(C[C@H](F)C6)CCC7
Biological Activity: (1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(1R)-KRAS inhibitor-24 | 98.29% | (1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R. | ||||||||||||||||||||
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Keywords
