3031412-82-2

HER2-IN-15 Chemical Structure
3031412-82-2

Chemical Structure

HER2-IN-15

  • CAS No.: 3031412-82-2
  • Formula:C28H29N9O2
  • Molecular Weight:523.59

InChIKey: XXIFAQMVDXYDNY-SNAWJCMRSA-N

SMILES: CC1=CC(NC2=NC=NN3C=CC(C4CN(C4)C(/C=C/CN(C)C)=O)=C23)=CC=C1OC5=CC6=NC=NN6C=C5

Biological Activity: HER2-IN-15 (Compound 1) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-15 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC)[1].

Cat. No. Product Name Purity Description Pricing
HY-163417
HER2-IN-15 HER2-IN-15 (Compound 1) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-15 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC).
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