3033961-38-2
3033961-38-2
Chemical Structure
BEN-28010
- CAS No.: 3033961-38-2
- Formula:C20H22N8
- Molecular Weight:374.44
InChIKey: MSQDCBLMCCHPQS-GOSISDBHSA-N
SMILES: CN(C)[C@H](CC1)CN1C(C=C2)=CC=C2N(C=N3)C=C3NC4=NC=C(C#N)N=C4
Biological Activity: BEN-28010 is a selective, orally active, blood-brain barrier permeable CHK1 inhibitor with an IC50 of 4.0 nM. BEN-28010 functions as a radiosensitizer, exhibits antitumor efficacy in GBM models. BEN-28010 can be used for the research of glioblastoma[1].
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BEN-28010 | BEN-28010 is a selective, orally active, blood-brain barrier permeable CHK1 inhibitor with an IC50 of 4.0 nM. BEN-28010 functions as a radiosensitizer, exhibits antitumor efficacy in GBM models. BEN-28010 can be used for the research of glioblastoma. | |||||||||||||||||||||
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References
Keywords
