3034310-17-0

GSPT1 degrader-9 Chemical Structure
3034310-17-0

Chemical Structure

GSPT1 degrader-9

  • CAS No.: 3034310-17-0
  • Formula:C37H36ClN7O5
  • Molecular Weight:694.18

InChIKey: JIWPWTFFRDWHRI-UHFFFAOYSA-N

SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CC(CCN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C4)C=C3C2=O)=O)=O

Biological Activity: GSPT1 degrader-9 (Compound F) is a cereblon-based molecular glue degrader for G1 to S phase transition protein 1 (GSPT1) that degrades GSPT1 with a rate of 95% (1 μM) GSPT1 and 86% (0.1 μM). GSPT1 degrader-9 inhibits the cell viability of HL-60 with an IC50 of 9.2 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-159609
GSPT1 degrader-9 GSPT1 degrader-9 (Compound F) is a cereblon-based molecular glue degrader for G1 to S phase transition protein 1 (GSPT1) that degrades GSPT1 with a rate of 95% (1 μM) GSPT1 and 86% (0.1 μM). GSPT1 degrader-9 inhibits the cell viability of HL-60 with an IC50 of 9.2 nM.
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