3035557-55-9
Chemical Structure
diABZI-V/C-Mal
- CAS No.: 3035557-55-9
- Formula:C67H83N19O14
- Molecular Weight:1378.49
InChIKey: KCKAGKNQDSKAFR-ZPQFPFFXSA-N
SMILES: O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCNC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C8=CC(C)=NN8CC)=O
Biological Activity: diABZI-V/C-Mal is a STING agonist (with a STING EC50 of 314 nM in TH1 dual reporter cells) and a Cathepsin B substrate. diABZI-V/C-Mal activates STING, thereby triggering the IRF3 signaling pathway. diABZI-V/C-Mal is cleaved by Cathepsin B to regenerate diABZI-NH2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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diABZI-V/C-Mal | 99.28% | diABZI-V/C-Mal is a STING agonist (with a STING EC50 of 314 nM in TH1 dual reporter cells) and a Cathepsin B substrate. diABZI-V/C-Mal activates STING, thereby triggering the IRF3 signaling pathway. diABZI-V/C-Mal is cleaved by Cathepsin B to regenerate diABZI-NH2. | ||||||||||||||||||||
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Keywords
